Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-β-Lactamases and Penicillin-Binding Proteins | ACS Chemical Biology
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The structures of penicillin-binding protein 4 (PBP4) and PBP5 from Enterococci provide structural insights into β-lactam resistance - Journal of Biological Chemistry
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Antibiotics | Free Full-Text | Glycosyltransferases and Transpeptidases/ Penicillin-Binding Proteins: Valuable Targets for New Antibacterials
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Structural and mechanistic basis of penicillin-binding protein inhibition by lactivicins | Nature Chemical Biology
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The Penicillin-Binding Protein PbpP Is a Sensor of β-Lactams and Is Required for Activation of the Extracytoplasmic Function σ Factor σP in Bacillus thuringiensis | mBio
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Antibiotics | Free Full-Text | Glycosyltransferases and Transpeptidases/ Penicillin-Binding Proteins: Valuable Targets for New Antibacterials
Osmosis - 💊 Penicillins belong to the pharmacological group of beta-lactam #antibiotics. These all have a beta-lactam ring in their structure, and work by inhibiting cell wall synthesis in bacteria, like Borrelia
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An alternative penicillin-binding protein involved in Salmonella relapses following ceftriaxone therapy - eBioMedicine
β-Lactam Resistance Response Triggered by Inactivation of a Nonessential Penicillin-Binding Protein | PLOS Pathogens
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Active site restructuring regulates ligand recognition in class A penicillin -binding proteins | PNAS
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